Center for Catalytic Hydrocarbon functionalizations

Silylative Reductive Amination of α,β-Unsaturated Aldehydes: A Convenient Synthetic Route to β-Silylated Secondary Amines

Eunae Kim, Sehoon Park and Sukbok Chang [Chem. Eur. J 24, 5765-5769(2018)]

Selective formation of γ-lactams via C–H amidation enabled by tailored iridium catalysts

Seung Youn Hong†, Yoonsu Park†, Yeongyu Hwang, Yeong Bum Kim, Mu-Hyun Baik, and Sukbok Chang (†: equally contributed) [Science 359, 1016-1021(2018)]

Reductive Carbocyclization of Homoallylic Alcohols to syn-Cyclobutanes by a Boron-Catalyzed Dual Ring-Closing Pathway

Chinmoy K. Hazra, Jinhoon Jeong, Hyunjoong Kim, Mu-Hyun Baik, Sehoon Park, and Sukbok Chang [Angew. Chem. Int. Ed 57(10), 2692-2696(2018)]

Iridium-catalysed arylation of C–H bonds enabled by oxidatively induced reductive elimination

Kwangmin Shin, Yoonsu Park, Mu-Hyun Baik, and Sukbok Chang [Nat. Chem 10, 218-224(2018)]

Visible Light-Promoted Synthesis of Spiroepoxy Chromanone Derivatives via A Tandem Oxidation/Radical Cyclization/Epoxidation Process

Jung, S.; Kim, J.; Hong, S. [Adv. Synth. Catal 359, 3945-(2017)]

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Fascaplysin exerts anti-cancer effects through the suppression of survivin and HIF-1α by inhibiting RTK-mediated mTOR-4EBP1 pathways

Oh, T.-I; Lee, Y.-M.; Ko, Y.-S; Mah, S.; Kim, J.; Kim, Y.; Reddy, R. H.; Kim, Y. J.; Hong, S.; Lim, J.-H. [Int. J. Mol. Sci. 18, 2074-(2017)]

Identification of 4-Phenoxyquinoline Based Inhibitors for L1196M Mutant of ALK by Structure-Based Design

Mah, S.; Park, J. H.; Jung, H.-Y.; Ahn, K.; Choi, S.; Tae, H. S.; Jung, K. H.; Rho, J. K.; Lee, J. C.; Hong, S-S.; Hong, S. [J. Med. Chem. 60, 9205-(2017)]

Discovery of EGF Receptor Inhibitors that are Selective for the d746-750/T790M/C797S Mutant through Structure-Based de Novo Design

Kim, I.; Min, M.; Kang, D.; Kim, K.; Hong, S. [Angew. Chem. Int. Ed. 56, 7637-(2017)]